Article
Global gene expression profiling and tissue microarray reveal novel candidate genes and down-regulation of the tumor suppressor gene CAV1 in sporadic vestibular schwannomas.
Neurosurgery - 1 Oct 2010
Aarhus Mads, Bruland Ove, Sætran Hege Aase, Mork Sverre J, Lund-Johansen Morten, Knappskog Per M
Abstract excerpt
BACKGROUND: The vestibular nerve is the predilection site for schwannomas. Few transcriptomic studies have been performed on solely sporadic vestibular schwannomas (VSs). OBJECTIVE: To detect genes with altered expression levels in sporadic VSs. METHODS: We studied 25 VSs and 3 tibial nerves (controls) with the ABI 1700 microarray platform. Significance analysis of microarrays was performed to explore...
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