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Article

HLA typing in a Kenyan cohort identifies novel class I alleles that restrict cytotoxic T-cell responses to local HIV-1 clades.

AIDS (London, England) - 27 Sept 2002

Bird Thomas G, Kaul Rupert, Rostron Timothy, Kimani Joshua, Embree Joanne, Dunn Paul P, Bwayo Job J, Plummer Francis A, Rowland-Jones Sarah L, Dong Tao

Abstract excerpt

OBJECTIVES: To investigate HLA class I allele frequencies in a Kenyan commercial sex worker (CSW) cohort, and to examine HIV-1 specific cytotoxic T lymphocyte (CTL) responses directed against epitopes derived from locally prevalent clade A virus. METHODS: PCR-single strand polymorphism HLA class I typing. Sequencing of novel alleles and examination of their distribution in the CSW cohort, and a low risk HIV...

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Share to Epitopes, T-Lymphocyte
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single-Stranded Conformational

Share to Sequence Analysis

Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 12351949
DOI: 10.1097/00002030-200209270-00006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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