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Repeated jaundice due to YMDD mutant in a patient with prolonged lamivudine therapy for chronic hepatitis B under prednisolone treatment for Still's disease.

Internal medicine (Tokyo, Japan) - 1 Sept 2002

Joh Riho, Hasegawa Kiyoshi, Torii Nobuyuki, Ogawa Miho, Kanai Naoko, Naritomi Takuma, Ishikawa Kayo, Iizuka Aiko, Shizuma Toru, Hashimoto Etsuko, Hayashi Naoaki

Abstract excerpt

A 50-year-old woman patient began receiving lamivudine because of acute exacerbation of chronic hepatitis B. She also suffered from adult-onset Still's disease and had received prednisolone for 5 years. Lamivudine was effective for treatment of the first flare. Fifteen months after lamivudine treatment was started, a breakthrough due to lamivudine-resistant strain M5521 occurred. Between 10 and 12 months after...

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Identifiers

PMID: 12322795
DOI: 10.2169/internalmedicine.41.701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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