Article
Lamivudine therapy for Japanese patients with cirrhosis B.
Intervirology - 1 Jan 2003
Okanoue Takeshi, Mori Kojiro, Kirishima Toshihiko, Kunimoto Koji, Yasui Kohichiroh, Itoh Yoshito, Minami Masahito
Abstract excerpt
OBJECTIVE: The aim of this study was to investigate the emergence of YMDD mutants in patients with chronic hepatitis B during lamivudine therapy and to compare the emergence patterns of YMDD mutants in cirrhotic and noncirrhotic patients. METHODS: Eighteen cirrhotic and 37 noncirrhotic patients with chronic hepatitis B were studied. The emergence of YMDD mutants was determined before, as well as at 1, 3, 6, 9 and...
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