Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical impact of the development of YMDD mutants in hepatitis B virus-associated glomerulonephritis.

Hepato-gastroenterology - 1 Jan 2000

Gwak Geum-Youn, Lee Choon Young, Lee Dong Ho, Huh Wooseong, Koh Kwang Cheol, Kim Yoon-Goo

Abstract excerpt

BACKGROUND/AIMS: Elimination of chronic viral infection with lamivudine (LAM) has recently been proposed to induce remission of HBV-associated glomerulonephritis (GN). However, prolonged LAM therapy can lead to the development of LAM-resistant HBV, causing viral breakthrough in serum. The present study evaluated the effect of the development of YMDD mutations on renal disease in HBV-associated GN patients....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Directed DNA Polymerase
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerulonephritis

Share to Hepatitis B, Chronic

Share to Hepatitis B virus

Share to Lamivudine

Share to Mutation

Source

Identifiers

PMID: 21937397
DOI: 10.5754/hge07389

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical impact of the development of YMDD mutants in hepatitis B virus-associated glomerulonephritis.PMID 21937397Read ↗

The incidence and clinical outcome of YMDD mutants in hepatitis B surface antigen-positive renal allograft recipients after prolonged lamivudine therapy.Semantic proximity Read ↗

Long-term follow-up study of Chinese patients with YMDD mutations: significance of hepatitis B virus genotypes and characteristics of biochemical flares.Semantic proximity Read ↗

Correlation of the occurrence of YMDD mutations with HBV genotypes, HBV-DNA levels, and HBeAg status in Chinese patients with chronic hepatitis B during lamivudine treatment.Semantic proximity Read ↗

Evolution of wild type and mutants of the YMDD motif of hepatitis B virus polymerase during lamivudine therapy.Semantic proximity Read ↗

Clinical features of chronic hepatitis B patients with YMDD mutation after lamivudine therapy.Semantic proximity Read ↗

Virological and biochemical relapse according to YMDD motif mutant type during long-term lamivudine monotherapy.Semantic proximity Read ↗

Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy.Semantic proximity Read ↗

Rapid re-emergence of YMDD mutation of hepatitis B virus with hepatic decompensation after lamivudine retreatment.Semantic proximity Read ↗

Comparison of clinical outcome between patients continuing and discontinuing lamivudine therapy after biochemical breakthrough of YMDD mutants.Semantic proximity Read ↗

Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistant mutants during prolonged lamivudine therapy.Semantic proximity Read ↗

[Natural YMDD motif mutations of HBV polymerase in the chronic hepatitis B virus infected patients].Semantic proximity Read ↗

HBV GENOTYPIC RESISTANCE TO LAMIVUDINE IN KIDNEY RECIPIENTS AND HEMODIALYZED PATIENTSSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.