Article
Interferon therapy for flare-up of hepatitis B virus infection after emergence of lamivudine-induced YMDD motif mutant.
Journal of gastroenterology - 1 Feb 2001
Someya T, Suzuki Y, Arase Y, Kobayashi M, Suzuki F, Tsubota A, Saitoh S, Chayama K, Murashima N, Ikeda K, Kumada H
Abstract excerpt
A 61-year-old man with chronic hepatitis B was treated with interferon (IFN)-alpha for flare-up after the emergence of a lamivudine-induced YMDD motif mutant. The YMDD mutant emerged 13 months after the initiation of lamivudine therapy. Despite this, lamivudine therapy was continued. Acute exacer...
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