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Article

Long-term follow-up study of Chinese patients with YMDD mutations: significance of hepatitis B virus genotypes and characteristics of biochemical flares.

Journal of clinical microbiology - 1 Sept 2004

Yuen Man-Fung, Yuan He-Jun, Sablon Erwin, Wong Danny Ka-Ho, Chan Annie On-On, Wong Benjamin Chun-Yu, Lai Ching-Lung

Abstract excerpt

We sought to examine the role of hepatitis B virus (HBV) genotypes in virological breakthroughs and biochemical flares in patients with YMDD mutations during lamivudine therapy. Virologic breakthroughs (i.e., the reappearance of HBV DNA as determined by bDNA assay) and biochemical flares (mild flares = alanine aminotransferase [ALT] between 2 and 10 times the upper limit of normal [ULN]; severe flares = ALT >10...

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Identifiers

PMID: 15364971
DOI: 10.1128/JCM.42.9.3932-3936.2004
PMCID: PMC516364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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