Article
Pseudoknot-dependent translational coupling in repBA genes of the IncB plasmid pMU720 involves reinitiation.
Journal of bacteriology - 1 Oct 2002
Praszkier J, Pittard A J
Abstract excerpt
Replication of the IncB miniplasmid pMU720 requires synthesis of the replication initiator protein, RepA, whose translation is coupled to that of a leader peptide, RepB. The unusual feature of this system is that translational coupling in repBA has to be activated by the formation of a pseudoknot immediately upstream of the repA Shine-Dalgarno sequence. A small antisense RNA, RNAI, controls replication of pMU720...
Topics
- Bacterial Proteins
- Base Pairing
- Base Sequence
- Codon, Initiator
- Codon, Terminator
- DNA Helicases
- DNA Replication
- DNA-Binding Proteins
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Molecular Sequence Data
- Mutation
- Plasmids
- Protein Biosynthesis
- Proteins
- RNA, Bacterial
- RNA, Messenger
- Ribosomes