Article
Single Strand Conformation Polymorphism (SSCP) as a quick and reliable method to genotype M235T polymorphism of angiotensinogen gene.
Clinical biochemistry - 1 Jul 2002
Bettinaglio Paola, Galbusera Andrea, Caprioli Jessica, Orisio Silvia, Perna Annalisa, Arnoldi Federica, Bucchioni Sara, Noris Marina
Abstract excerpt
OBJECTIVES: Conflicting results on the relationship between M235T polymorphism of angiotensinogen (AGT) gene and diabetic nephropathy are reported in the literature, probably due to the small number of subjects, to different inclusion criteria and the different genotype analysis methods used. The aim of the present study was to set up a fast, cheap and reliable method to allow the genotyping of M235T polymorphism...
Topics
- Adult
- Aged
- Alleles
- Angiotensinogen
- Base Sequence
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Female
- Genetic Testing
- Genotype
- Humans
- Hypertension
- Male
- Middle Aged