Article
Identification and characterization of a novel promoter of the mouse mu opioid receptor gene (Oprm) that generates eight splice variants.
Gene - 24 Jul 2002
Pan Ying-Xian
Abstract excerpt
Our previous studies isolated and characterized eight splicing variants containing exon 11 as the first coding exon. The location of exon 11 about 10 kb upstream from exon 1 dual promoters implied another promoter to drive expression of the exon 11 variants. I now identify the second promoter in the 5'-flanking region of exon 11. One major transcriptional start point was determined. Sequence analysis indicated...
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