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Article

High-throughput tissue microarray analysis of 11q13 gene amplification (CCND1, FGF3, FGF4, EMS1) in urinary bladder cancer.

The Journal of pathology - 1 Dec 2003

Zaharieva Boriana M, Simon Ronald, Diener Pierre-Andre, Ackermann Daniel, Maurer Robert, Alund Göran, Knönagel Hartmut, Rist Marcus, Wilber Kim, Hering Franz, Schönenberger Andreas, Flury Renata, Jäger Peter, Fehr Jean Luc, Mihatsch Michael J, Gasser Thomas, Sauter Guido, Toncheva Draga I

Abstract excerpt

Gene amplification is a common mechanism for oncogene overexpression. High-level amplifications at 11q13 have been repeatedly found in bladder cancer by comparative genomic hybridization (CGH) and other techniques. Putative candidate oncogenes located in this region are CCND1 (PRAD1, bcl-1), EMS1, FGF3 (Int-2), and FGF4 (hst1, hstf1). To evaluate the involvement of these genes in bladder cancer, a tissue...

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Source

Identifiers

PMID: 14648664
DOI: 10.1002/path.1481

Genes

CCND1
FGF4
FGF3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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High-throughput tissue microarray analysis of 11q13 gene amplification (CCND1, FGF3, FGF4, EMS1) in urinary bladder cancer.PMID 14648664Read ↗

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