Article
New insights into intracellular lipid binding proteins: The role of buried water.
Protein science : a publication of the Protein Society - 1 Oct 2002
Lücke Christian, Huang Sinian, Rademacher Martin, Rüterjans Heinz
Abstract excerpt
The crystal structures of most intracellular lipid binding proteins (LBPs) show between 5 and 20 internally bound water molecules, depending on the presence or the absence of ligand inside the protein cavity. The structural and functional significance of these waters has been discussed for several LBPs based on studies that used various biophysical techniques. The present work focuses on two very different LBPs,...
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