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Article

Case study of hydrogen bonding in a hydrophobic cavity.

The journal of physical chemistry. B - 18 Dec 2014

Chen Yi-Chen, Cheng Chao-Sheng, Tjong Siu-Cin, Yin Hsien-Sheng, Sue Shih-Che

Abstract excerpt

Protein internal hydrogen bonds and hydrophobicity determine protein folding and structure stabilization, and the introduction of a hydrogen bond has been believed to represent a better interaction for consolidating protein structure. We observed an alternative example for chicken IL-1β. The native IL-1β contains a hydrogen bond between the Y157 side-chain OηH and I133 backbone CO, whereby the substitution from...

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Source

Identifiers

PMID: 25412145
DOI: 10.1021/jp5097053

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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