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Article

Multiplexed, high-throughput genotyping by single-base extension and end-labeled free-solution electrophoresis.

Analytical chemistry - 1 Sept 2002

Vreeland Wyatt N, Meagher Robert J, Barron Annelise E

Abstract excerpt

Technologies that allow for high-throughput, economical, and accurate single nucleotide polymorphism (SNP) genotyping are becoming crucial for modern genomic efforts. Here, we present a method for multiplexed single-base extension (SBE) genotyping that takes advantage of the unique separation modalities made possible via end-labeled free-solution electrophoresis (ELFSE). Three unique SBE oligonucleotide primers,...

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PMID: 12236339
DOI: 10.1021/ac0258094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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