[Beta-amyloid protein: recent progress in basic research and therapeutic approaches].

Abstract excerpt

Deposition of amyloid beta protein (A beta) as senile plaques or cerebrovascular amyloid characterizes the brains of patients with Alzheimer's disease (AD). A beta are composed of 40-42 amino acids that are proteolytically produced from its precursor beta APP. We have shown that the deposition of A beta ending at the 42nd residue (A beta 42) is one of the earliest pathological changes in AD brains. Genetic and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amyloid beta-Peptides
• Share to Amyloid beta-Protein Precursor
• Share to Amyloid Precursor Protein Secretases