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Article

[Alzheimer's disease: basic aspects].

Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics - 1 Mar 2000

Iwatsubo T

Abstract excerpt

The deposition of amyloid beta peptides (A beta) in one of the pathological hallmarks of Alzheimer's disease (AD). A beta are composed of 40-42 amino acid peptides that are proteolytically cleaved from beta amyloid precursor proteins (beta APP). The deposition as diffuse plaques of a species of A beta ending at the 42nd residue residue (A beta 42) is one of the earliest pathological changes of AD. Importantly,...

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Source

Identifiers

PMID: 10879068
DOI: 10.3143/geriatrics.37.207

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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