Relationship of the Glyoxylate Pathway to the Pathogenesis of <i>Cryptococcus neoformans</i>

Abstract excerpt

Functional genomics has become a major focus in the study of microbial pathogenesis. This study used a functional genomic tool, differential display reverse transcription-PCR, to identify a transcriptional profile of Cryptococcus neoformans cells as they produced meningitis in an immunosuppressed host. This serial global gene expression during infection allowed for the identification of up- and down-regulated...

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