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Article

A key role of the hSNF5/INI1 tumour suppressor in the control of the G1-S transition of the cell cycle.

Oncogene - 19 Sept 2002

Versteege Isabella, Medjkane Souhila, Rouillard Danny, Delattre Olivier

Abstract excerpt

The hSNF5/INI1 gene encodes a member of the SWI/SNF chromatin remodelling complexes. It was recently identified as a tumour suppressor gene mutated in sporadic and hereditary Malignant Rhabdoid Tumours (MRT). However, the role of hSNF5/INI1 loss-of-function in tumour development is still unknown. Here, we show that the ectopic expression of wild-type hSNF5/INI1, but not that of truncated versions, leads to a cell...

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PMID: 12226744
DOI: 10.1038/sj.onc.1205841

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CDC6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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A key role of the hSNF5/INI1 tumour suppressor in the control of the G1-S transition of the cell cycle.PMID 12226744Read ↗

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