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Article

TNF contributes to the immunopathology of perforin/Fas ligand double deficiency.

Immunology and cell biology - 1 Oct 2002

Cretney Erika, Street Shayna E A, Smyth Mark J

Abstract excerpt

Perforin (pfp)/Fas ligand (FasL) double-deficient mice have previously been shown to be infertile, lose weight and die prematurely due to tissue destruction caused by a significant inflammatory infiltrate of monocytes/macrophages and T cells. Herein we have compared disease progression in mice ad...

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Source

Identifiers

PMID: 12225379
DOI: 10.1046/j.1440-1711.2002.01108.x

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12225379-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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