Article
Calcineurin, a calcium/calmodulin-dependent protein phosphatase, is involved in movement, fertility, egg laying, and growth in Caenorhabditis elegans.
Molecular biology of the cell - 1 Sept 2002
Bandyopadhyay Jaya, Lee Jiyeon, Lee Jungsoo, Lee Jin Il, Yu Jae-Ran, Jee Changhoon, Cho Jeong-Hoon, Jung Sunki, Lee Myon Hee, Zannoni Sonia, Singson Andrew, Kim Do Han, Koo Hyeon-Sook, Ahnn Joohong
Abstract excerpt
Calcineurin is a Ca(2+)-calmodulin-dependent serine/threonine protein phosphatase that has been implicated in various signaling pathways. Here we report the identification and characterization of calcineurin genes in Caenorhabditis elegans (cna-1 and cnb-1), which share high homology with Drosophila and mammalian calcineurin genes. C. elegans calcineurin binds calcium and functions as a heterodimeric protein...
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