Article
Two isoforms of sarco/endoplasmic reticulum calcium ATPase (SERCA) are essential in Caenorhabditis elegans.
Gene - 31 Dec 2000
Cho J H, Bandyopadhyay J, Lee J, Park C S, Ahnn J
Abstract excerpt
SERCA (Sarco/Endoplasmic Reticulum Calcium ATPase), a membrane bound Ca(2+)- /Mg(2+)- dependent ATPase that sequesters Ca(2+) into the SR/ER lumen, is one of the essential components for the maintenance of intracellular Ca(2+) homeostasis. Here we describe the identification and functional characterization of a C. elegans SERCA gene (ser-1). ser-1 is a single gene alternatively spliced at its carboxyl terminus to...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Caenorhabditis elegans
- Calcium-Transporting ATPases
- Embryo, Nonmammalian
- Embryonic Development
- Gene Expression Regulation, Enzymologic
- Green Fluorescent Proteins
- Isoenzymes
- Luminescent Proteins
- Microscopy, Fluorescence
- Molecular Sequence Data