Article
Calcineurin regulates coelomocyte endocytosis via DYN-1 and CUP-4 in Caenorhabditis elegans.
Molecules and cells - 1 Sept 2010
Song Hyun-Ok, Lee Jungsoo, Ji Yon Ju, Dwivedi Meenakshi, Cho Jeong Hoon, Park Byung-Jae, Ahnn Joohong
Abstract excerpt
C. elegans coelomocytes are macrophage-like scavenger cells that provide an excellent in vivo system for the study of clathrin-mediated endocytosis. Using this in vivo system, several genes involved in coelomocyte endocytosis have been identified previously. However, the detailed mechanism of endocytic pathway is still unknown. Here, we report a new function of calcineurin, an evolutionarily conserved...
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