Article
Role of fission yeast Tup1-like repressors and Prr1 transcription factor in response to salt stress.
Molecular biology of the cell - 1 Sept 2002
Greenall Amanda, Hadcroft Andrew P, Malakasi Panagiota, Jones Nic, Morgan Brian A, Hoffman Charles S, Whitehall Simon K
Abstract excerpt
In Schizosaccharomyces pombe, the Sty1 mitogen-activated protein kinase and the Atf1 transcription factor control transcriptional induction in response to elevated salt concentrations. Herein, we demonstrate that two repressors, Tup11 and Tup12, and the Prr1 transcription factor also function in the response to salt shock. We find that deletion of both tup genes together results in hypersensitivity to elevated...
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