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Article

Fission yeast global repressors regulate the specificity of chromatin alteration in response to distinct environmental stresses.

Nucleic acids research - 1 Jan 2004

Hirota Kouji, Hasemi Tomoko, Yamada Takatomi, Mizuno Ken-ich, Hoffman Charles S, Shibata Takehiko, Ohta Kunihiro

Abstract excerpt

The specific induction of genes in response to distinct environmental stress is vital for all eukaryotes. To study the mechanisms that result in selective gene responses, we examined the role of the fission yeast Tup1 family repressors in chromatin regulation. We found that chromatin structure around a cAMP-responsive element (CRE)-like sequence in ade6-M26 that is bound by Atf1.Pcr1 transcriptional activation...

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Identifiers

PMID: 14762213
DOI: 10.1093/nar/gkh251
PMCID: PMC373364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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