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Article

Response of fission yeast to toxic cations involves cooperative action of the stress-activated protein kinase Spc1/Sty1 and the Hal4 protein kinase.

Molecular and cellular biology - 1 May 2005

Wang Ling-Yu, Shimada Koichi, Morishita Masayo, Shiozaki Kazuhiro

Abstract excerpt

Stress-activated protein kinases (SAPKs), members of a mitogen-activated protein kinase (MAPK) subfamily, are highly conserved among eukaryotes. Studies of yeasts demonstrated that SAPKs play pivotal roles in survival responses to high osmolarity, oxidative stress, and heat shock. Here we report a novel physiological role of the fission yeast Spc1 SAPK in cellular resistance to certain cations, such as Na(+),...

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Source

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Identifiers

PMID: 15870269
DOI: 10.1128/MCB.25.10.3945-3955.2005
PMCID: PMC1087739

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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