Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resistance mutations in HIV-infected patients experiencing early failure with nelfinavir-containing triple combinations.

Medical science monitor : international medical journal of experimental and clinical research - 1 Sept 2002

Núńez Marina, de Mendoza Carmen, Valer Luisa, Casas Esperanza, López-Calvo Soledad, Castro Angeles, Rosón Beatriz, Podzamczer Daniel, Rubio Amalia, Berenguer Juan, Soriano Vincent

Abstract excerpt

BACKGROUND: The purpose of our study was to assess the presence of nelfinavir (NFV)-associated resistance mutations at the time of early virological failure in subjects receiving NFV as part of a first protease inhibitor (PI)-based triple regimen. MATERIAL/METHODS: Subjects failing their first PI-based NFV-containing triple regimen were identified in six Spanish hospitals. HIV genotyping was carried out in plasma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance
Share to Genes, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HIV Protease

Share to HIV Protease Inhibitors

Share to HIV Reverse Transcriptase

Share to HIV Seropositivity

Share to Nelfinavir

Source

Identifiers

PMID: 12218942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resistance mutations in HIV-infected patients experiencing early failure with nelfinavir-containing triple combinations.PMID 12218942Read ↗

Diverse pattern of protease inhibitor resistance mutations in HIV-1 infected patients failing nelfinavir.Semantic proximity Read ↗

Primary nelfinavir (NFV)-associated resistance mutations during a follow-up period of 108 weeks in protease inhibitor naïve patients treated with NFV-containing regimens in an HIV clinic cohort.Semantic proximity Read ↗

Drug resistance mutations and outcome of second-line treatment in patients with first-line protease inhibitor failure on nelfinavir-containing HAART.Semantic proximity Read ↗

Drug resistance mutations in HIV-1-infected subjects during protease inhibitor-containing highly active antiretroviral therapy with nelfinavir or indinavir.Semantic proximity Read ↗

Prevalence of HIV protease mutations on failure of nelfinavir-containing HAART: a retrospective analysis of four clinical studies and two observational cohorts.Semantic proximity Read ↗

Antiretroviral Resistance After First-Line Antiretroviral Therapy Failure in Diverse HIV-1 Subtypes in the SECOND-LINE Study.Semantic proximity Read ↗

HIV-1 genotype resistance pattern and evolution in patients failing nelfinavir-containing regimens.Semantic proximity Read ↗

Mechanisms of early virologic failure in antiretroviral-naive patients starting protease inhibitor-containing regimens: the APROVIR Study.Semantic proximity Read ↗

Indinavir plasma concentrations and resistance mutations in patients experiencing early virological failure.Semantic proximity Read ↗

Virologic response to nelfinavir-based regimens: pharmacokinetics and drug resistance mutations (VIRAPHAR study).Semantic proximity Read ↗

Emerging mutations at virological failure of HAART combinations containing tenofovir and lamivudine or emtricitabine.Semantic proximity Read ↗

Phenotypic cross-resistance to nelfinavir: the role of prior antiretroviral therapy and the number of mutations in the protease gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.