Article
Diverse pattern of protease inhibitor resistance mutations in HIV-1 infected patients failing nelfinavir.
Journal of medical virology - 1 Aug 2005
Svedhem Veronica, Lindkvist A, Bergroth T, Knut Lidman, Sönnerborg A
Abstract excerpt
The aim of the study was to describe the pattern of resistance mutations in human immunodeficiency virus type 1 (HIV-1) infected patients experiencing their first protease inhibitor (PI) failure on nelfinavir (NFV)-containing therapy. Earlier PI-naïve patients (n=172) with NFV-containing therapy were therefore retrospectively studied. Plasma HIV RNA from 43 failing patients was sequenced. In addition, virus from...
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