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Article

Cutting edge: susceptibility to psoriatic arthritis: influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles.

Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2002

Martin Maureen P, Nelson George, Lee Jeong-Hee, Pellett Fawnda, Gao Xiaojiang, Wade Judith, Wilson Michael J, Trowsdale John, Gladman Dafna, Carrington Mary

Abstract excerpt

NK cell activity is partially controlled through interactions between killer Ig-like receptors (KIR) on NK cells and their respective HLA class I ligands. Independent segregation of HLA and KIR genes, along with KIR specificity for particular HLA allotypes, raises the possibility that any given individual may express KIR molecules for which no ligand is present. Inhibitory receptor genes KIR2DL2/3 and KIR2DL1...

Read the complete abstract on PubMed

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Share to Arthritis, Psoriatic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12218090
DOI: 10.4049/jimmunol.169.6.2818

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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