Article
Deletion of the activating <scp>NKG</scp>2C receptor and a functional polymorphism in its ligand <scp>HLA</scp>‐E in psoriasis susceptibility
23 Aug 2013
Abstract excerpt
Psoriasis is an inflammatory, immune-mediated disease of the skin. Several studies have suggested that natural killer (NK) cells and their receptors may be important for its pathogenesis. Here, we examined whether deletion of the activating natural killer receptor gene NKG2C, which has a frequency of 20% in the European population, was associated with psoriasis susceptibility. The NKG2C deletion and a functional...
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