Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distinct HLA-C/KIR genotype profile associates with guttate psoriasis.

The Journal of investigative dermatology - 1 Oct 2005

Holm Sofia J, Sakuraba Kazuko, Mallbris Lotus, Wolk Katarina, Ståhle Mona, Sánchez Fabio O

Abstract excerpt

Psoriasis is a multifactorial disease with a strong genetic background. It associates strongly to HLA-Cw*0602. HLA-C interacts with killer immunoglobulin-like receptors (KIR) on natural killer (NK) and some natural killer-T (NKT) cells. KIR's function is triggered by specific binding to HLA ligands, which depends on the amino acid 80 of the MHC class I alpha-chain. This permits classifying all HLA-C alleles into...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-C Antigens

Share to Psoriasis

Share to Receptors, Immunologic

Share to Receptors, KIR

Source

Identifiers

PMID: 16185272
DOI: 10.1111/j.0022-202X.2005.23879.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distinct HLA-C/KIR genotype profile associates with guttate psoriasis.PMID 16185272Read ↗

HLA-C and guttate psoriasis.Semantic proximity Read ↗

Human Leukocyte Antigen-Class I Alleles and the Autoreactive T Cell Response in Psoriasis Pathogenesis.Semantic proximity Read ↗

Cutting edge: susceptibility to psoriatic arthritis: influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles.Semantic proximity Read ↗

Diversity of KIR/HLA Genotypes and Their Association with Psoriasis Vulgaris in the Western Mexican Population.Semantic proximity Read ↗

HLA-Cw6 and psoriasis.Semantic proximity Read ↗

Gene for the activating natural killer cell receptor, KIR2DS1, is associated with susceptibility to psoriasis vulgaris.Semantic proximity Read ↗

Association of variably expressed KIR3dl1 alleles with psoriatic disease.Semantic proximity Read ↗

The HLA-Cw12 Allele Is an Important Susceptibility Allele for Psoriasis and Is Associated with Resistant Psoriasis in the Turkish PopulationSemantic proximity Read ↗

Emerging role for the killer-cell immunoglobulin-like receptors genotype, in the susceptibility of skin diseases.Semantic proximity Read ↗

HLA-Cw*0602 associates with a twofold higher prevalence of positive streptococcal throat swab at the onset of psoriasis: a case control study.Semantic proximity Read ↗

Cross-sectional study reveals that HLA-C*07:02 is a potential biomarker of early onset/lesion severity of psoriasis.Semantic proximity Read ↗

Cutting edge: heterozygote advantage in autoimmune disease: hierarchy of protection/susceptibility conferred by HLA and killer Ig-like receptor combinations in psoriatic arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.