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Article

Neuropilin1 regulates glomerular function and basement membrane composition through pericytes in the mouse kidney.

Kidney international - 1 Apr 2017

Wnuk Monika, Anderegg Manuel A, Graber Werner A, Buergy Regula, Fuster Daniel G, Djonov Valentin

Abstract excerpt

Neuropilin1 (Nrp1) is a co-receptor best known to regulate the development of endothelial cells and is a target of anticancer therapies. However, its role in other vascular cells including pericytes is emergent. The kidney is an organ with high pericyte density and cancer patients develop severe proteinuria following administration of NRP1B-neutralizing antibody combined with bevacizumab. Therefore, we...

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Identifiers

PMID: 27988210
DOI: 10.1016/j.kint.2016.10.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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