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Article

Human papillomavirus and p53 mutational status as prognostic factors in head and neck carcinoma.

Head & neck - 1 Sept 2002

Sisk Elizabeth A, Soltys Scott G, Zhu Shaobo, Fisher Susan G, Carey Thomas E, Bradford Carol R

Abstract excerpt

BACKGROUND: Mutations of the p53 tumor-suppressor gene are common in squamous cell carcinoma of the head and neck (SCCHN) and may portend a worse prognosis. Human papillomavirus (HPV) represents another potential prognostic factor for SCCHN. The oncogenic potential of HPV may be due to the ability of its E6 oncoprotein to promote degradation of wild-type p53 protein. We wish to determine whether there is a lower...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12211048
DOI: 10.1002/hed.10146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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