Article
Contribution of the interleukin-1beta gene polymorphism in multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society - 1 Jul 2002
Nishimura Masataka, Kawakami Hideshi, Komure Osamu, Maruyama Hirofumi, Morino Hiroyuki, Izumi Yuishin, Nakamura Shigenobu, Kaji Ryuji, Kuno Sadako
Abstract excerpt
We studied genetic polymorphisms in the promoter region at position -511 of the interleukin (IL) -1beta gene (IL-1B-511) and at position -889 of the IL-1alpha gene (IL-1A-889), in 111 Japanese patients with multiple system atrophy (MSA) and 160 controls. The distribution of IL-1B-511 was significantly different between MSA patients and controls, because of the under-representation of patients with homozygotes for...
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