Article
Interleukin-1A (-889) genetic polymorphism increases the risk of multiple system atrophy.
Movement disorders : official journal of the Movement Disorder Society - 1 Nov 2003
Combarros Onofre, Infante Jon, Llorca Javier, Berciano José
Abstract excerpt
In a case-control study using a clinically well-defined group of 30 multiple system atrophy (MSA) patients and 110 control subjects, homozygosity for interleukin-1A (IL-1A) allele 2 (high secretor of proinflammatory cytokine) in the regulatory region (-889) of the IL-1A gene was associated with a fivefold increased risk for MSA.
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