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Article

Human dendritic cell deficiency: the missing ID?

Nature reviews. Immunology - 19 Aug 2011

Collin Matthew, Bigley Venetia, Haniffa Muzlifah, Hambleton Sophie

Abstract excerpt

Animal models and human in vitro systems indicate that dendritic cells (DCs) have a crucial role in priming naive T cells, but just how important are they in the intact human? Recent descriptions of human DC deficiency have begun to shed light on this question and to illuminate other puzzles of human DC biology, including their haematopoietic origin, developmental regulation and homeostatic equilibrium with other...

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PMID: 21852794
DOI: 10.1038/nri3046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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