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Article

Drug-induced long-QT syndrome associated with a subclinical SCN5A mutation.

Circulation - 3 Sept 2002

Makita Naomasa, Horie Minoru, Nakamura Takeshi, Ai Tomohiko, Sasaki Koji, Yokoi Hisataka, Sakurai Masayuki, Sakuma Ichiro, Otani Hideo, Sawa Hirofumi, Kitabatake Akira

Abstract excerpt

BACKGROUND: Subclinical mutations in genes associated with the congenital long-QT syndromes (LQTS) have been suggested as a risk factor for drug-induced LQTS and accompanying life-threatening arrhythmias. Recent studies have identified genetic variants of the cardiac K+ channel genes predisposing affected individuals to acquired LQTS. We have identified a novel Na+ channel mutation in an individual who exhibited...

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Source

Identifiers

PMID: 12208804
DOI: 10.1161/01.cir.0000027139.42087.b6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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