Article
Phenotypic analysis of mice deficient in the major myelin protein MOBP, and evidence for a novel Mobp isoform.
Glia - 1 Sept 2002
Yool D, Montague P, McLaughlin M, McCulloch M C, Edgar J M, Nave K-A, Davies R W, Griffiths I R, McCallion A S
Abstract excerpt
Myelin-associated oligodendrocytic basic protein (MOBP) is a recently identified major component of central nervous system (CNS) myelin. We previously reported a detailed characterization of the genomic region encompassing the Mobp gene, elucidating the complex series of transcript splicing responsible for the generation of its diverse family of protein isoforms. These basic, positively charged polypeptides...
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