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Article

The dynamics of T-lymphocyte responses during combination therapy for chronic hepatitis C virus infection.

Hepatology (Baltimore, Md.) - 1 Sept 2002

Barnes Eleanor, Harcourt Gillian, Brown Dave, Lucas Michaela, Phillips Rodney, Dusheiko Geoffrey, Klenerman Paul

Abstract excerpt

Hepatitis C virus (HCV) readily sets up a persistent infection and is a major cause of liver disease worldwide. Interferon alfa and ribavirin therapy lead to sustained clearance of virus in 31% to 64% of patients with type 1 and non-type 1 genotypes, respectively. It is not clear to what extent these drugs act directly to reduce HCV replication, or indirectly via host immune responses, and what evoked immune...

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Source

Identifiers

PMID: 12198669
DOI: 10.1053/jhep.2002.35344

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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