Article
Immune responses in hepatitis C virus infection and mechanisms of hepatitis C virus persistence.
Journal of gastroenterology and hepatology - 1 Oct 2008
Hiroishi Kazumasa, Ito Takayoshi, Imawari Michio
Abstract excerpt
Immune responses against hepatitis C virus (HCV) play a crucial role in the pathogenesis of chronic hepatitis C. HCV infection often persists and leads to chronic hepatitis and eventually cirrhosis. Accumulated data suggest that HCV proteins suppress host immune responses through the suppression of functions of immune cells, such as cytotoxic T lymphocytes, natural killer cells, and dendritic cells. They also...
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