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Article

Hepatitis C virus-specific T-cell reactivity during interferon and ribavirin treatment in chronic hepatitis C.

Gastroenterology - 1 Feb 2000

Cramp M E, Rossol S, Chokshi S, Carucci P, Williams R, Naoumov N V

Abstract excerpt

BACKGROUND & AIMS: The role of virus-specific T-helper lymphocyte reactivity in determining the therapeutic response in chronic hepatitis C virus (HCV) infection is not fully understood. METHODS: We studied CD4(+) T lymphocyte proliferation together with interferon (IFN)-gamma and interleukin (IL)-10 production from peripheral blood mononuclear cells in response to 4 HCV antigens (core, NS3, NS4, and NS5) in 25...

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Identifiers

PMID: 10648463
DOI: 10.1016/s0016-5085(00)70217-4

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