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The magnitude and breadth of hepatitis C virus-specific CD8+ T cells depend on absolute CD4+ T-cell count in individuals coinfected with HIV-1.

Blood - 1 Feb 2005

Kim Arthur Y, Lauer Georg M, Ouchi Kei, Addo Marylyn M, Lucas Michaela, Schulze Zur Wiesch Julian, Timm Joerg, Boczanowski Melinda, Duncan Jared E, Wurcel Alysse G, Casson Deborah, Chung Raymond T, Draenert Rika, Klenerman Paul, Walker Bruce D

Abstract excerpt

CD8(+) T-cell responses are an essential antiviral host defense in persistent viral infections, and their sustained effectiveness is thought to be critically dependent on CD4(+) T-helper cells. To determine the relationship between HIV-1-induced CD4(+) T-cell depletion and hepatitis C virus (HCV)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15459014
DOI: 10.1182/blood-2004-06-2336

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15459014-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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