Article
The specificity of phenotypic induction of mouse and human stem cells by signaling complexes.
In vitro cellular & developmental biology. Animal - 1 Apr 2002
Dai Jianwu, Kumar Janardan, Feng Yajun, Asrican Rose, Kim Jung, Fofonoff Timothy, Russakovsky Vladimir, Churchill Ryan, Roy Niloy, Bell Eugene
Abstract excerpt
Controlling the specific differentiation of stem cells (SCs) is a goal sought by many because of the benefits it would yield for repair or replacement of damaged tissues and organs. We report the discovery of signaling complexes and describe their use in predictably guiding the differentiation of mouse and human SCs. The signaling complexes (Signal-plexes [S-ps]) induce mouse and human SCs to express specific...
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