Article
Endophilin is critically required for synapse formation and function in Drosophila melanogaster.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Sept 2002
Rikhy Richa, Kumar Vimlesh, Mittal Rohit, Krishnan K S
Abstract excerpt
Studies in cell-free systems and the lamprey giant synapse have implicated crucial roles for amphiphysin and endophilin in synaptic transmission. However, null mutants at the amphiphysin locus of Drosophila are viable and have no demonstrable synaptic vesicle-recycling defect. This has necessitated a re-examination of the role of Src homology 3 domain-containing proteins in synaptic vesicle recycling. In this...
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