Article
Endophilin functions as a membrane-bending molecule and is delivered to endocytic zones by exocytosis.
Cell - 29 Oct 2010
Bai Jihong, Hu Zhitao, Dittman Jeremy S, Pym Edward C G, Kaplan Joshua M
Abstract excerpt
Two models have been proposed for endophilin function in synaptic vesicle (SV) endocytosis. The scaffolding model proposes that endophilin's SH3 domain recruits essential endocytic proteins, whereas the membrane-bending model proposes that the BAR domain induces positively curved membranes. We sh...
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