Article
GSTM-1 and NAT2 and genetic alterations in colon tumors.
Cancer causes & control : CCC - 1 Aug 2002
Slattery M L, Curtin Karen, Ma K, Schaffer Donna, Potter John, Samowitz Wade
Abstract excerpt
OBJECTIVE: Phase II metabolizing enzymes such as glutathione S-transferases and N-acetyltransferase are involved in the detoxification of carcinogens. Genetic variants of genes coding for these enzymes have been evaluated as to their association with colon cancer, both as independent risk factors and as effect modifiers for associations with diet and cigarette smoking. In this study, we evaluate associations...
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