Article
Quantitative measurement of the splice variants 120 and 164 of the angiogenic peptide vascular endothelial growth factor in the time flow of fracture healing: a study in the rat.
Cell and tissue research - 1 Sept 2002
Pufe Thomas, Wildemann Britt, Petersen Wolf, Mentlein Rolf, Raschke Michael, Schmidmaier Gerhard
Abstract excerpt
Formation of new blood vessels is essential for the process of wound and fracture healing. Little is known about the time-dependent expression and the involved splice variants of the vascular endothelial growth factor (VEGF). We therefore quantified and differentiated the angiogenic factor VEGF and its receptors (VEGFR) in a rat fracture model by immunohistochemical, biochemical and molecular biological methods....
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