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Adenoviral expression of vascular endothelial growth factor splice variants differentially regulate bone marrow‐derived mesenchymal stem cells

20 Feb 2008

Abstract excerpt

Bone marrow-derived mesenchymal stem cells (MSCs) are being explored for clinical applications, and genetic engineering represents a useful strategy for boosting the therapeutic potency of MSCs. Vascular endothelial growth factor (VEGF)-based gene therapy protocols have been used to treat tissue ischemia, and a combined VEGF/MSC therapeutics is appealing due to their synergistic paracrine actions. However,...

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PMID: 18288639
DOI: 10.1002/jcp.21414

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