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Article

Superior angiogenic potential of GDF-5 and GDF-5(V453/V456) compared with BMP-2 in a rabbit long-bone defect model.

The Journal of bone and joint surgery. American volume - 15 Oct 2014

Kleinschmidt Kerstin, Wagner-Ecker Mechthild, Bartek Benjamin, Holschbach Jeannine, Richter Wiltrud

Abstract excerpt

BACKGROUND: The clinical application of bone morphogenetic proteins such as BMP-2 and GDF-5 (growth and differentiation factor-5) may improve the outcome of bone defect repair. In addition to the osteoinductivity of BMPs, their angiogenic potential is important as an adequate blood supply is a pr...

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Source

Identifiers

PMID: 25320196
DOI: 10.2106/JBJS.M.01462

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25320196-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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