Article
Regulators of Vps4 ATPase activity at endosomes differentially influence the size and rate of formation of intralumenal vesicles.
Molecular biology of the cell - 15 Mar 2010
Nickerson Daniel P, West Matthew, Henry Ryan, Odorizzi Greg
Abstract excerpt
Recruitment of endosomal sorting complexes required for transport (ESCRTs) to the cytosolic face of endosomes regulates selective inclusion of transmembrane proteins into the lumenal vesicles of multivesicular bodies (MVBs). ESCRT-0, -I, and -II bind directly to ubiquitinated transmembrane cargoe...
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