Article
Serotonin transporter gene promoter variants do not explain the hyperserotoninemia in autistic children.
Molecular psychiatry - 1 Jan 2002
Persico A M, Pascucci T, Puglisi-Allegra S, Militerni R, Bravaccio C, Schneider C, Melmed R, Trillo S, Montecchi F, Palermo M, Rabinowitz D, Reichelt K-L, Conciatori M, Marino R, Keller F
Abstract excerpt
Autism is a biologically-heterogeneous disease. Distinct subgroups of autistic patients may be marked by intermediate phenotypes, such as elevated serotonin (5-HT) blood levels, potentially associated with different underlying disease mechanisms. This could lead to inconsistent genetic association results, such as those of prior studies on serotonin transporter (5-HTT) gene promoter variants and autistic...
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